2. Academic Validation
  3. Applications of immunohistochemistry

Applications of immunohistochemistry

  • J Pharm Bioallied Sci. 2012 Aug;4(Suppl 2):S307-9. doi: 10.4103/0975-7406.100281.
Jeyapradha Duraiyan 1,  Rajeshwar Govindarajan,  Karunakaran Kaliyappan,  Murugesan Palanisamy
Affiliations

Affiliation

  • 1 Department of Oral and Maxillofacial Pathology, Thai Moogambigai Dental College & Hospital, Chennai, India.
PMID: 23066277 DOI: 10.4103/0975-7406.100281
Abstract

Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal Antibodies to determine the tissue distribution of an antigen of interest in health and disease. IHC is widely used for diagnosis of cancers; specific tumor antigens are expressed de novo or up-regulated in certain cancers. This article deals with the various applications of IHC in diagnosis of diseases, with IHC playing an important role in diagnostic and research laboratories.

Keywords

Antibody; antigen; disease; immunohistochemistry.

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