2. Academic Validation
  3. Cardioprotective effect of resveratrol and resveratroloside

Cardioprotective effect of resveratrol and resveratroloside

  • Cardiovasc Hematol Agents Med Chem. 2013 Sep;11(3):207-10. doi: 10.2174/187152571103140120103302.
Sergey E Naumenko,  Tatiana V Latysheva,  Michael A Gilinsky,  Artem D Rogachev,  Nina I Komarova,  Nariman F Salakhutdinov,  Genrikh A Tolstikov 1
Affiliations

Affiliation

  • 1 Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 630090, Novosibirsk, Russia. [email protected].
PMID: 23547903 DOI: 10.2174/187152571103140120103302
Abstract

Cardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received resveratroloside). The cardioprotective effect of resveratroloside was detected for the first time.

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