1. Academic Validation
  2. New clerodane diterpenes from Tinospora sagittata var. yunnanensis

New clerodane diterpenes from Tinospora sagittata var. yunnanensis

  • Planta Med. 2014 Mar;80(5):419-25. doi: 10.1055/s-0034-1368252.
Zhi-Yong Jiang 1 Wen-Juan Li 1 Li-Xiang Jiao 1 Jun-Ming Guo 1 Kai Tian 1 Chun-Tao Yang 1 Xiang-Zhong Huang 1
Affiliations

Affiliation

  • 1 Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming, Yunnan, P. R. China.
Abstract

Four new clerodane diterpenes, namely sagittatayunnanosides A-D (1-4), were isolated from the roots of Tinospora sagittata var. yunnanensis, together with two known compounds, tinospinoside C (5) and tinospinoside E (6). The structures of the four new compounds were well elucidated by extensive analyses of the MS, IR, and 1D and 2D NMR data. The cytotoxic and antifouling activities of compounds 1-6 were evaluated.

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