2. Academic Validation
  3. Imidazopyridines as a source of biological activity and their pharmacological potentials-Infrared and Raman spectroscopic evidence of their content in pharmaceuticals and plant materials

Imidazopyridines as a source of biological activity and their pharmacological potentials-Infrared and Raman spectroscopic evidence of their content in pharmaceuticals and plant materials

  • Bioorg Med Chem. 2015 Sep 15;23(18):6087-99. doi: 10.1016/j.bmc.2015.07.045.
Lucyna Dymińska 1
Affiliations

Affiliation

  • 1 Department of Bioorganic Chemistry, Institute of Chemistry and Food Technology, Faculty of Engineering and Economics, Wrocław University of Economics, 118/120 Komandorska, 53-345 Wrocław, Poland. Electronic address: [email protected].
PMID: 26314922 DOI: 10.1016/j.bmc.2015.07.045
Abstract

Derivatives of imidazopyridine are used in medicinal chemistry due to their biological and pharmaceutical properties. This review article presents imidazopyridine pharmacological activity as antiinflammatory, Anticancer, Antiviral, antiosteoporotic, antiparasitic, and antihypertensive agents by studying its various synthesized derivatives. Some of compounds with imidazopyridine skeleton are used in psychiatry and autoimmune disorders. The presented data suggest that IR and Raman spectra measurements are a good methods for identification and characterization of the compounds containing imidazopyridine core. Two stretching vibrations: νas(Φ) and νs(Φ) are of a diagnostic importance. The appearance of these bands in the IR and Raman spectra of some Plants, tissues and pharmaceuticals confirms the presence of imidazopyridine skeleton in these substances.

Keywords

IR and Raman spectra; Imidazopyridine.

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