1. Academic Validation
  2. Gout: optimizing treatment to achieve a disease cure

Gout: optimizing treatment to achieve a disease cure

  • Ther Adv Chronic Dis. 2016 Mar;7(2):135-44. doi: 10.1177/2040622315618393.
José Antonio Bernal 1 Neus Quilis 2 Mariano Andrés 2 Francisca Sivera 3 Eliseo Pascual 4
Affiliations

Affiliations

  • 1 Sección de Reumatología, Hospital General Universitario de Alicante, Pintor Baeza 12, Alicante, 03010, Spain.
  • 2 Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain.
  • 3 Sección de Reumatología, Hospital General Universitario de Elda, Alicante, Spain.
  • 4 Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain; Departamento de Medicina (Reumatología), Universidad Miguel Hernández, Alicante, Spain.
Abstract

Gout is one of the most common inflammatory arthritides. The disease is due to the deposition of monosodium urate crystals. These deposits are reversible with proper treatment, suggesting that gout is a curable disease. The main aim in gout is to lower serum uric acid levels to a pre-established target; there are different urate-lowering drugs (Xanthine Oxidase inhibitors, uricosurics and uricases) through which this can be achieved. Proper treatment of gout also involves correct management of acute flares and their prevention. To ensure treatment adherence it is necessary to explain to the patient what the objectives are.

Keywords

allopurinol; colchicine; gout; monosodium urate crystals; uric acid.

Figures