2. Academic Validation
  3. An antimicrobial peptide with an aggregation-induced emission (AIE) luminogen for studying bacterial membrane interactions and antibacterial actions

An antimicrobial peptide with an aggregation-induced emission (AIE) luminogen for studying bacterial membrane interactions and antibacterial actions

  • Chem Commun (Camb). 2017 Mar 16;53(23):3315-3318. doi: 10.1039/c6cc09408b.
Ning Ning Li 1,  Jun Zhi Li 1,  Peng Liu 2,  Dicky Pranantyo 2,  Lei Luo 3,  Jiu Cun Chen 1,  En-Tang Kang 2,  Xue Feng Hu 4,  Chang Ming Li 1,  Li Qun Xu 1
Affiliations

Affiliations

  • 1 Institute for Clean Energy and Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing, 400715, China. [email protected] [email protected].
  • 2 Department of Chemical & Biomolecular Engineering, National University of Singapore, 117576, Singapore.
  • 3 College of Pharmaceutical Science, Southwest University, Chongqing, 400715, China.
  • 4 National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China. [email protected].
PMID: 28078346 DOI: 10.1039/c6cc09408b
Abstract

A fluorescence technique to investigate the interactions between Bacterial membranes and an aggregation-induced emission (AIE) luminogen-decorated AMP (TPE-AMP) was reported. Our simple and fast method consists of mixing TPE-AMP and Bacterial suspensions and recording the fluorescence signals by flow cytometry and confocal microscopy in a "non-washing" manner.

Figures
Products