2. Academic Validation
  3. Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

  • Biomater Sci. 2019 Aug 20;7(9):3594-3598. doi: 10.1039/c9bm00152b.
Haw-Young Kwon 1,  Jun-Young Kim,  Xiao Liu,  Jung Yeol Lee,  Joey Kuok Hoong Yam,  Louise Dahl Hultqvist,  Wang Xu,  Morten Rybtke,  Tim Tolker-Nielsen,  Wooseok Heo,  Jong-Jin Kim,  Nam-Young Kang,  Taiha Joo,  Liang Yang,  Sung-Jin Park,  Michael Givskov,  Young-Tae Chang
Affiliations

Affiliation

  • 1 Center for Self-assembly and Complexity, Institute for Basic Science (IBS), Pohang 37673, Republic of Korea. [email protected].
PMID: 31329200 DOI: 10.1039/c9bm00152b
Abstract

Detection of the biofilm of bacteria would be a counter strategy to detect hidden bacteria in their camouflage. Through unbiased screening of bacteria biofilm, we discovered a long wavelength probe CDr15 with extracellular DNA as the molecular target. CDr15 revealed a real-time geometric distribution of eDNA in a 3D Bacterial colony.

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