2. Academic Validation
  3. Toxicity of tetracycline and its transformation products to a phosphorus removing Shewanella strain

Toxicity of tetracycline and its transformation products to a phosphorus removing Shewanella strain

  • Chemosphere. 2020 May;246:125681. doi: 10.1016/j.chemosphere.2019.125681.
Sha Long 1,  Yongkui Yang 2,  Spyros G Pavlostathis 3,  Feng Xiang 2,  Peizhe Sun 2,  Na Li 4,  Lin Zhao 5
Affiliations

Affiliations

  • 1 School of Environmental Science and Engineering, Tianjin University, Tianjin, 300072, China; School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA, 30332-0512, USA.
  • 2 School of Environmental Science and Engineering, Tianjin University, Tianjin, 300072, China.
  • 3 School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA, 30332-0512, USA.
  • 4 Central Laboratory of Tianjin Academy of Agricultural Sciences, Tianjin, 300381, China.
  • 5 School of Environmental Science and Engineering, Tianjin University, Tianjin, 300072, China. Electronic address: [email protected].
PMID: 31896014 DOI: 10.1016/j.chemosphere.2019.125681
Abstract

Tetracycline (TC) as an emerging contaminant has raised serious concerns about its toxicity and removal in wastewater treatment processes. The more toxic transformation products of TC, 4-epitetracycline (ETC), anhydrotetracycline (ATC) and 4-epianhydrotetracycline (EATC) are also widely detected. This study investigated the Antibacterial and bactericidal activity of TC, ETC, ATC, EATC against Shewanella sp, using Escherichia coli and Pseudomonas aeruginosa strains as quality controls. Further, batch assays were conducted to investigate the inhibition of these Antibiotics on the phosphorus removal of the Shewanella strain, and removal mechanisms of TC and its transformation products (TCs). The inhibition on phosphorus removal by the Shewanella strain at 20 mg L-1 was in the order of ATC > EATC > TC > ETC. COD removal, poly-P accumulation and glycogen synthesis by the Shewanella strain were also inhibited. Biodegradation was the main removal mechanism of TC and ETC, while adsorption was the main one of ATC and EATC. This study helps to further understand the structure-activity relationship of TC.

Keywords

Antibacterial activity; Inhibition; Phosphorus removal; Shewanella; Tetracycline; Transformation products.

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