1. Academic Validation
  2. Peptide Blocking Self-Polymerization of Extracellular Calcium-Sensing Receptor Attenuates Hypoxia-Induced Pulmonary Hypertension

Peptide Blocking Self-Polymerization of Extracellular Calcium-Sensing Receptor Attenuates Hypoxia-Induced Pulmonary Hypertension

  • Hypertension. 2021 Nov;78(5):1605-1616. doi: 10.1161/HYPERTENSIONAHA.120.16712.
Rui Xiao 1 2 Shengquan Luo 1 2 Ting Zhang 1 2 Yankai Lv 2 3 Tao Wang 2 4 Jiwei Zhang 5 Yuan Su 2 6 Matthieu Ruiz 7 8 Jocelyn Dupuis 8 9 Liping Zhu  # 1 2 Qinghua Hu  # 1 2
Affiliations

Affiliations

  • 1 From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.).
  • 2 Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).
  • 3 Department of Pathology (Y.L.), Tongji Hospital.
  • 4 Department of Respiratory and Critical Care Medicine (T.W.), Tongji Hospital.
  • 5 Department of Pathology (J.Z.).
  • 6 Department of Respiratory and Critical Care Medicine, Union Hospital (Y.S.).
  • 7 Tongji Medical College, Huazhong University of Science and Technology (HUST), China; Department of Nutrition, Université de Montréal, Canada (M.R.).
  • 8 Montreal Heart Institute, Canada (M.R., J.D.).
  • 9 Department of medicine, Université de Montréal, Canada (J.D.).
  • # Contributed equally.
Abstract

[Figure: see text].

Keywords

body weight; hypoxia; plasma; polymerization; pulmonary hypertension.

Figures
Products
  • Cat. No.
    Product Name
    Description
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  • HY-10374
    99.96%, Flk-1/KDR Inhibitor