2. Academic Validation
  3. NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL-1β and co-localizing with NLRP3 in trans-Golgi to alleviate pathogenic bacteria-induced colitis

NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL-1β and co-localizing with NLRP3 in trans-Golgi to alleviate pathogenic bacteria-induced colitis

  • Clin Transl Med. 2021 Dec;11(12):e639. doi: 10.1002/ctm2.639.
Zhao Deng 1,  Zhipeng Yang 1,  Chenbin Cui 1,  Hongkui Wei 1,  Lijia Wang 2,  Dean Tian 2,  Fang Xiao 2,  Jian Peng 1 3
Affiliations

Affiliations

  • 1 Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, P. R. China.
  • 2 Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, China.
  • 3 The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, Hubei, 430070, China.
PMID: 34923769 DOI: 10.1002/ctm2.639
Figures
Products