2. Academic Validation
  3. RG7388 inhibits SFTSV replication by suppressing MDM2-mediated p53 degradation and preventing apoptosome disruption

RG7388 inhibits SFTSV replication by suppressing MDM2-mediated p53 degradation and preventing apoptosome disruption

  • Sci Bull (Beijing). 2026 Jan 15;71(1):55-59. doi: 10.1016/j.scib.2025.06.028.
Zixiang Liu 1,  Mengqian Huang 1,  Yuyang Liu 1,  Luna Cui 1,  Xixi Shi 1,  Honghua Chen 1,  Xiaoning Gao 1,  Zining Wang 1,  Qinting Lin 1,  Zhiyun Wang 2,  Yue Teng 3,  Tao Wang 4
Affiliations

Affiliations

  • 1 School of Life Sciences, Tianjin University, Tianjin 300072, China.
  • 2 School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China; Tianjin Key Laboratory of Pathogenic Microbiology of Infectious Disease, Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China. Electronic address: [email protected].
  • 3 State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, China. Electronic address: [email protected].
  • 4 School of Life Sciences, Tianjin University, Tianjin 300072, China; State Key Laboratory of Synthetic Biology, Tianjin University, Tianjin 300072, China. Electronic address: [email protected].
PMID: 40619297 DOI: 10.1016/j.scib.2025.06.028
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