2. Academic Validation
  3. (-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer

(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer

  • Biol Proced Online. 2025 Dec 5. doi: 10.1186/s12575-025-00312-2.
Zhen-Yu Zhao # 1,  Jian-Chun Wu # 1,  Ying-Bin Luo 1,  Yu-Li Wang 1,  Xi Wang 1,  Jian-Hui Tian 1,  Bo Zhang 2,  Yan Li 3
Affiliations

Affiliations

  • 1 Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.
  • 2 Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China. [email protected].
  • 3 Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China. [email protected].
  • # Contributed equally.
PMID: 41350836 DOI: 10.1186/s12575-025-00312-2
Keywords

(-)-Guaiol; CD36; CPT1; Lewis lung cancer; PPAR-γ.

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