1. Academic Validation
  2. Activity of brodimoprim and metioprim alone and in combination with sulfonamides against anaerobic bacteria

Activity of brodimoprim and metioprim alone and in combination with sulfonamides against anaerobic bacteria

  • Antimicrob Agents Chemother. 1983 Mar;23(3):490-2. doi: 10.1128/AAC.23.3.490.
J Wüst J Schwarzenbach
Abstract

The activities of the 2,4-diamino-5-benzylpyrimidines brodimoprim and metioprim against anaerobic bacteria were tested alone and in combination with sulfonamides. Alone they were two to four times more active than trimethoprim, but in combination with sulfonamides, their activity was slightly lower than that of trimethoprim plus sulfamethoxazole.

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