2. Academic Validation
  3. New taxanes from Taxus brevifolia

New taxanes from Taxus brevifolia

  • J Nat Prod. 1982 Jul-Aug;45(4):466-70. doi: 10.1021/np50022a019.
D G Kingston,  D R Hawkins,  L Ovington
PMID: 7130988 DOI: 10.1021/np50022a019
Abstract

The isolation of two taxanes from Taxus brevifolia Nutt. is described, together with the isolation of two acetylated taxol derivatives from an acetylated fraction from the same plant. The compounds were identified on the basis of their spectroscopic properties as taxa-4(20),11-diene-2 alpha, 5 alpha, 7 beta, 9 alpha, 10 beta, 13 alpha-hexaol 2,7,9,10,13-pentaacetate (1) (decinnamoyltaxinine J), 10-deacetylbaccatin III (2), taxol 2',7-diacetate (3), and 10-deacetyltaxol 2',7-diacetate (4).

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