2. Academic Validation
  3. Two bioactive pterocarpans from Erythrina burana

Two bioactive pterocarpans from Erythrina burana

  • J Nat Prod. 1993 Oct;56(10):1831-4. doi: 10.1021/np50100a028.
E Dagne 1,  A A Gunatilaka,  D G Kingston,  M Alemu,  G Hofmann,  R K Johnson
Affiliations

Affiliation

  • 1 Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061-0212.
PMID: 8277323 DOI: 10.1021/np50100a028
Abstract

Bioactivity-directed fractionation of the CHCl3 extract of the bark of Erythrina burana afforded phaseollidin [1] and cristacarpin [2]. Both 1 and 2 exhibited moderate but selective activity towards DNA repair-deficient yeast mutants, whereas only 1 was found to be cytotoxic. 13C-nmr spectra of both compounds were assigned.

Figures