2. Academic Validation
  3. A human cDNA encoding the 110-kDa A subunit of RNA polymerase II transcription factor elongin

A human cDNA encoding the 110-kDa A subunit of RNA polymerase II transcription factor elongin

  • Gene. 1996 Feb 12;168(2):277-8. doi: 10.1016/0378-1119(95)00750-4.
T Aso 1,  D Haque,  K Fukudome,  C S Brower,  J W Conaway,  R C Conaway
Affiliations

Affiliation

  • 1 Program in Molecular and Cell Biology, Oklahoma Medical Research Foundation, Oklahoma City 73104, USA.
PMID: 8654961 DOI: 10.1016/0378-1119(95)00750-4
Abstract

A full-length cDNA encoding a human homolog of the approx. 110-kDa subunit (elongin A; El A) of the RNA polymerase II transcription factor, elongin, was isolated and sequenced. Comparison of the open reading frames of the human el A cDNA and the previously characterized rat El A cDNA [Aso et al., Science 269 (1995) 1439-1443] indicates that they are 84% conserved in nucleotide sequence and encode 84% identical proteins.

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