2. Academic Validation
  3. Molecular cloning and expression of human chondroitin 6-sulfotransferase

Molecular cloning and expression of human chondroitin 6-sulfotransferase

  • Biochim Biophys Acta. 1998 Jul 30;1399(1):57-61. doi: 10.1016/s0167-4781(98)00089-x.
M Fukuta 1,  Y Kobayashi,  K Uchimura,  K Kimata,  O Habuchi
Affiliations

Affiliation

  • 1 Department of Life Science, Aichi University of Education, Japan.
PMID: 9714738 DOI: 10.1016/s0167-4781(98)00089-x
Abstract

Using cDNA of chick chondroitin 6-sulfotransferase (C6ST), human C6ST cDNA has been isolated. The amino acid sequence of human C6ST displayed 74% identity to chick C6ST. The major difference in amino acid sequence between chick C6ST and human C6ST was the presence of a unique hydrophilic domain in human C6ST. A 7.8-kb message of C6ST was expressed ubiquitously in various human adult tissues, indicating a rather diverse function of C6ST.

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