2. Academic Validation
  3. A new bromopyrrole alkaloid and the optical resolution of the racemate from the marine sponge homaxinella sp

A new bromopyrrole alkaloid and the optical resolution of the racemate from the marine sponge homaxinella sp

  • J Nat Prod. 1998 Nov;61(11):1433-4. doi: 10.1021/np980207u.
A Umeyama 1,  S Ito,  E Yuasa,  S Arihara,  T Yamada
Affiliations

Affiliation

  • 1 Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770, Japan, and Osaka University of Pharmaceutical Sciences 4-20-1, Nasahara, Takatsuki, Osaka 569-1041, Japan.
PMID: 9834174 DOI: 10.1021/np980207u
Abstract

A new bromopyrrole alkaloid (1) along with (+/-)-2 and (+/-)-longamide (3) has been isolated from the Japanese marine Sponge Homaxinella sp. The structures of the compounds were proposed on the basis of spectroscopic data. The optical resolution of (+/-)-2 by chiral HPLC was successful and afforded the two enantiomers, (+)-2 and (-)-2.

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