Nanatinostat (Synonyms: CHR-3996)

Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC₅₀ of 8 nM.

For research use only. We do not sell to patients.

Nanatinostat Chemical Structure

CAS No. : 1256448-47-1

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Description	Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC₅₀ of 8 nM^[1].
IC₅₀ & Target	IC50：8 nM ( HDAC)^[1]
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
References	[1]. Moffat D, et al. Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor. J Med Chem. 2010 Dec 23;53(24):8663-78.

Molecular Weight	394.40
Formula	C₂₀H₁₉FN₆O₂
CAS No.	1256448-47-1
SMILES	FC1=CC=C2N=C(CN[[email protected]]3[[email protected]]4([H])CN(C5=NC=CC(C(NO)=O)=N5)C[[email protected]]34[H])C=CC2=C1
Shipping	Room temperature in continental US; may vary elsewhere

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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