1. GPCR/G Protein
    Immunology/Inflammation
  2. CCR
  3. PF-04634817

PF-04634817 

Cat. No.: HY-117621
Handling Instructions

PF-0463481, an oral CCR2/5 dual antagonist, with a favorable ocular safety profile versus intravitreal therapies. PF-0463481 is safe and well-tolerated and being developed for the treatment of diabetic nephropathy.

For research use only. We do not sell to patients.

PF-04634817 Chemical Structure

PF-04634817 Chemical Structure

CAS No. : 1228111-63-4

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1 mg USD 80 In-stock
Estimated Time of Arrival: December 31
5 mg USD 230 Get quote
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Based on 1 publication(s) in Google Scholar

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Description

PF-0463481, an oral CCR2/5 dual antagonist, with a favorable ocular safety profile versus intravitreal therapies[1]. PF-0463481 is safe and well-tolerated and being developed for the treatment of diabetic nephropathy[2].

IC50 & Target[1]

CCR2

 

CCR5

 

Molecular Weight

511.58

Formula

C₂₅H₃₆F₃N₅O₃

CAS No.

1228111-63-4

SMILES

O=C(N1[[email protected]@]2([H])C[[email protected]@]([H])(C1)N(C3=NC=NC(C(F)(F)F)=C3)C2)[[email protected]@]4(C[[email protected]@H](CC4)N[[email protected]@H]5[[email protected]@H](COCC5)OC)C(C)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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PF-04634817
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HY-117621
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