Sodium phosphate dibasic dodecahydrate (Synonyms: Sodium phosphate dibasic dodecahydrate; Phosphoric acid disodium dodecahydrate)

製品番号: HY-Y1324 純度: 98.0%: Data Sheet SDS COA 取扱説明書
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Phosphoric acid disodium dodecahydrate is an inorganic compound and food additive. Phosphoric acid disodium dodecahydrate promotes gel formation, improves food texture and thermal properties of materials. Phosphoric acid disodium dodecahydrate induces glomerular calcification. Phosphoric acid disodium dodecahydrate can be used in kidney disease research.

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Sodium phosphate dibasic dodecahydrate 構造式

CAS 番号 : 10039-32-4

容量	価格（税別）	在庫状況	数量
1 g	$25	在庫あり	Estimated Time of Arrival: December 31
5 g	$50	在庫あり	Estimated Time of Arrival: December 31
10 g	$65	在庫あり	Estimated Time of Arrival: December 31
25 g	$110	在庫あり	Estimated Time of Arrival: December 31
50 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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製品説明

体外実験

Phosphoric acid disodium dodecahydrate (0.5-1.5 M) induces the gelation of thiolated citrus high-methoxyl pectin (TCHMP)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Phosphoric acid disodium (284-408 mg/kg; bolus i.v.; once daily; 14 days) dodecahydrate induces glomerular calcification, glomerular epithelial cell degeneration and proteinuria in Sprague-Dawley rats^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Sprague–Dawley rats (Jcl:SD), 5 weeks old^[3]
Dosage:	1, 28, 284, 408 mg/kg
Administration:	Intravenous bolus injection via the tail vein, once daily, for 14 days
Result:	Caused treatment-related proteinuria on days 7 and 13. Caused a pale kidney appearance. Caused the deposition of dense basophilic granules in the glomeruli (von Kossa-positive) and a dose-dependent degeneration of the glomerular and parietal epithelium. Caused podocyte fusion, increased microvilli, abundant debris in Bowman's spaces, and low-density lamellar structures in various parts of the glomerulus. Showed particles containing phosphorus and calcium mixed with a lamellar structure.

分子量

358.14

分子式

Na₂HPO₄·12H₂O

CAS 番号

10039-32-4

Appearance

<35°C Solid,>35°C Liquid

Color

White to off-white

SMILES

[Na2HPO4 ?12H2O]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Store at room temperature, keep dry and cool

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)

溶剤 & 溶解度

体外:

H₂O : 50 mg/mL (139.61 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7922 mL	13.9610 mL	27.9220 mL
5 mM	0.5584 mL	2.7922 mL	5.5844 mL
10 mM	0.2792 mL	1.3961 mL	2.7922 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 98.0%

Select Batch:

データシート (270 KB) SDS (394 KB)

COA (242 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Chen J, et al. The gelation behavior of thiolated citrus high-methoxyl pectin induced by sodium phosphate dibasic dodecahydrate. Carbohydr Polym. 2022;277:118849. [Content Brief]

[2]. Shen Z, et al. Use of cellulose nanofibril (CNF)/silver nanoparticles (AgNPs) composite in salt hydrate phase change material for efficient thermal energy storage. Int J Biol Macromol. 2021 Mar 31;174:402-412. [Content Brief]

[3]. Tsuchiya N, et al. Glomerular calcification induced by bolus injection with dibasic sodium phosphate solution in Sprague-Dawley rats. Toxicol Pathol. 2004 Jul-Aug;32(4):408-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.7922 mL	13.9610 mL	27.9220 mL	69.8051 mL
	5 mM	0.5584 mL	2.7922 mL	5.5844 mL	13.9610 mL
	10 mM	0.2792 mL	1.3961 mL	2.7922 mL	6.9805 mL
	15 mM	0.1861 mL	0.9307 mL	1.8615 mL	4.6537 mL
	20 mM	0.1396 mL	0.6981 mL	1.3961 mL	3.4903 mL
	25 mM	0.1117 mL	0.5584 mL	1.1169 mL	2.7922 mL
	30 mM	0.0931 mL	0.4654 mL	0.9307 mL	2.3268 mL
	40 mM	0.0698 mL	0.3490 mL	0.6981 mL	1.7451 mL
	50 mM	0.0558 mL	0.2792 mL	0.5584 mL	1.3961 mL
	60 mM	0.0465 mL	0.2327 mL	0.4654 mL	1.1634 mL
	80 mM	0.0349 mL	0.1745 mL	0.3490 mL	0.8726 mL
	100 mM	0.0279 mL	0.1396 mL	0.2792 mL	0.6981 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Sodium phosphate dibasic dodecahydrate Related Classifications

Endocrinology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量		濃度		体積		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）	×	体積 _（開始）	=	濃度 _（終了）	×	体積 _（終了）
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium phosphate dibasic dodecahydrate10039-32-4Disodium hydrogen phosphate dodecahydrate Disodium phosphate dodecahydrateBiochemical Assay ReagentsEnvironmental PollutantsEnvironmental ContaminantsSprague-Dawley ratsglomerular calcificationgelationfood additiveInhibitorinhibitorinhibit

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