1. Recombinant Proteins
  2. Receptor Proteins
  3. G-Protein-Coupled Receptors
  4. Rhodopsin-like receptors

Rhodopsin-like receptors

G Protein-Coupled Receptors (GPCRs), also called 7TM receptors, are the largest and most important integral membrane protein families, which mediate cellular responses to most hormones, metabolites, cytokines, and neurotransmitters, and therefore serve as “fruitful targets” for drug discovery. G Protein Coupled Receptors (GPCRs) perceive many extracellular signals and transduce them to heterotrimeric G proteins, which further transduce these signals intracellular to appropriate downstream effectors and thereby play an important role in various signaling pathways. GPCRs are categorized into six classes based on sequence and function: rhodopsin-like receptors (family A), secretin-like (family B), glutamate (family C), fungal mating pheromone receptors (Class D), cAMP receptors (Class E) and frizzled/smoothened (Class F). Class A GPCRs, rhodopsin-like receptors, is the largest group of GPCRs for a large variety of stimuli, which includes biogenic amine neurotransmitters, neuropeptides, peptide hormones, light, nucleotides, prostaglandins, leukotrienes, chemotactic peptides, and chemokines receptors. This family consists of 719 members and accounts for around 80% of GPCRs. The rhodopsin-like GPCRs show a conventional transmembrane domain (TMD) that forms ligand-binding pocket and additional eight helices with a palmitoylated cysteine at the C terminal.

Cat. No. Product Name / Synonyms Species Source
  • HY-P71730
    EDNRA Protein, Human (P.pastoris, His)

    Ednra; ET A; ET-A; ETA; ETA R; ETA-R; ETAR; ETRA; G protein coupled receptor; hET AR; hET-AR; MFDA

    Human P. pastoris
  • HY-P72138
    CHRM1 Protein, Rat (His)

    Chrm1; Chrm-1Muscarinic acetylcholine receptor M1

    Rat E. coli
  • HY-P72159
    CXCR4 Protein, Human (His-SUMO)

    C-X-C chemokine receptor type 4; CD184; CD184 antigen; Chemokine C X C motif; receptor 4; Chemokine CXC Motif Receptor 4; CXC-R4; CXCR-4; CXCR4; CXCR4_HUMAN; D2S201E; FB22; Fusin; HM89; HSY3RR; LAP 3; LAP3; LCR1; LESTR; Leukocyte derived seven transmembrane domain receptor; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide associated protein 3; Neuropeptide Y receptor Y3; NPY3R; NPYR; NPYRL; NPYY3; NPYY3R; Probable G protein coupled receptor lcr1 homolog; SDF 1 receptor; SDF-1 receptor; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR; Stromal cell derived factor 1 receptor; Stromal cell-derived factor 1 receptor; WHIM; WHIMS

    Human E. coli
  • HY-P72160
    CXCR4 Protein, Human (GST)

    C-X-C chemokine receptor type 4; CD184; CD184 antigen; Chemokine C X C motif; receptor 4; Chemokine CXC Motif Receptor 4; CXC-R4; CXCR-4; CXCR4; CXCR4_HUMAN; D2S201E; FB22; Fusin; HM89; HSY3RR; LAP 3; LAP3; LCR1; LESTR; Leukocyte derived seven transmembrane domain receptor; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide associated protein 3; Neuropeptide Y receptor Y3; NPY3R; NPYR; NPYRL; NPYY3; NPYY3R; Probable G protein coupled receptor lcr1 homolog; SDF 1 receptor; SDF-1 receptor; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR; Stromal cell derived factor 1 receptor; Stromal cell-derived factor 1 receptor; WHIM; WHIMS

    Human E. coli
  • HY-P72198
    FSHR Protein, Human (His)

    Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1

    Human E. coli
  • HY-P72674
    CXCR4 Protein, Human (HEK 293, Fc)

    C-X-C chemokine receptor type 4; CXC-R4; LESTR; LAP-3; NPYRL; CD184; SDF-1 receptor

    Human HEK293
  • HY-P74180
    EDNRB/Endothelin R Type B Protein, Human (HEK293, His)

    EDNRB; Endothelin receptor non-selective type; endothelin receptor type B; ETRB

    Human HEK293
  • HY-P74181
    EDNRB/Endothelin R Type B Protein, Human (HEK293, Fc)

    EDNRB; Endothelin receptor non-selective type; endothelin receptor type B; ETRB

    Human HEK293
  • HY-P76376
    GPR37 Protein, Human (HEK293, His)

    Prosaposin receptor GPR37; ETBR-LP-1; PAELR; GPR37

    Human HEK 293
Cat. No. Product Name Effect Purity