UBE2D4
UBE2D4 completes the UBE2D quartet and is the least studied member of the group. It retains the canonical UBC fold and active-site cysteine, is activated by UBA1, and collaborates with a range of RING and HECT E3 ligases in a manner overlapping its three paralogs. Expression is ubiquitous but generally lower than that of UBE2D1-D3, and functional redundancy among the four has hampered assignment of UBE2D4-specific physiological roles. Recombinant UBE2D4 is supplied mainly for comparative purposes: probing paralog preference of particular E3 enzymes, reconstituting polyubiquitin chain synthesis in vitro, and completing ubiquitin-pathway panels used in drug-discovery screening.
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UBE2D4 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
