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TYR

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Compare Product Name Species Source
  • HY-P78573
    PTK7 Protein, Cynomolgus/Rhesus macaque (HEK293, His)

    PTK7; CCK4; CCK-4; TYRosine-protein kinase-like 7; Protein-TYRosine kinase 7; Protein-TYRosine kinase 7

    		 Cynomolgus;Rhesus Macaque HEK293
    The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is the recombinant cynomolgus, Rhesus Macaque-derived PTK7 protein, expressed by HEK293 , with C-His labeled tag. The total length of PTK7 Protein, Cynomolgus/Rhesus macaque (HEK293, His) is 674 a.a., with molecular weight of 90-110 kDa.
  • HY-P77361
    EphB6 Protein, Cynomolgus (HEK293, Fc)

    Ephrin type-B receptor 6; HEP; TYRosine-protein kinase-defective receptor EPH-6; EPHB6

    		 Cynomolgus HEK293
    EphB6 is a member of the receptor tyrosine kinase family expressed primarily in thymic cells and T cell subpopulations. EphB6, when stimulated by ephrin-B2, inhibited JNK activation, and decreased T-cell receptor-induced IL-2 secretion and CD25 expression. EphB6 promotes colorectal epithelial cell transformation and may serve as a novel biomarker and therapeutic target for colorectal cancer. EphB6 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived EphB6 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphB6 Protein, Cynomolgus (HEK293, Fc) is 559 a.a., with molecular weight of 90-110 kDa.
  • HY-P77567
    AXL Protein, Cynomolgus (417a.a, HEK293, His)

    Axl; UFO; AXL oncogene; AXL; ARK; JTK11; TYRo7; AI323647; EC 2.7.10; EC 2.7.10.1

    		 Cynomolgus HEK293
    AXL Protein, a receptor tyrosine kinase, mediates signals by binding GAS6, regulating cell survival, proliferation, migration, and differentiation. Upon ligand binding, AXL undergoes dimerization and autophosphorylation, activating downstream molecules like PI3-kinase subunits, GRB2, PLCG1, and more. This triggers AKT kinase activation, influencing processes such as endothelial cell survival, cytokine signaling in NK cell development, hepatic regeneration, gonadotropin-releasing hormone neuron function, platelet activation, thrombotic responses, and immune modulation. AXL also serves as a receptor for lassa virus and lymphocytic choriomeningitis virus during microbial infection. AXL Protein, Cynomolgus (417a.a, HEK293, His) is the recombinant cynomolgus-derived AXL protein, expressed by HEK293 , with C-His labeled tag. The total length of AXL Protein, Cynomolgus (417a.a, HEK293, His) is 417 a.a., with molecular weight of 68-70 kDa.
  • HY-P700715
    EPHA5 Protein, Cynomolgus (HEK293, His)

    EHK-1; EK7; BSK; EHK1; HEK7; TYRO4; EphA5; Rek7; TYRO4HEK7CEK7

    		 Cynomolgus HEK293
    EPHA5 is a member of the erythropoietin-producing human liver cancer receptor (Eph receptor) that regulates embryogenesis by fine-tuning cell adhesion, localization, and migration, particularly in the nervous system. EPHA5 enhances the invasion and migration of esophageal squamous cell carcinoma through epithelial-mesenchymal transformation by activating the Wnt/β-catenin pathway. EPHA5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EPHA5 protein, expressed by HEK293 , with C-His labeled tag. The total length of EPHA5 Protein, Cynomolgus (HEK293, His) is 548 a.a., with molecular weight of 70-75 kDa.
  • HY-P700716
    EphB2 Protein, Cynomolgus (HEK293, His)

    DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3

    		 Cynomolgus HEK293
    The EphB2 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand on adjacent cells to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EphB2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB2 Protein, Cynomolgus (HEK293, His) is 524 a.a., with molecular weight of 65-75 kDa.
  • HY-P75804
    HER2/CD340 Protein, Cynomolgus (HEK293, Fc)

    Receptor TYRosine-protein kinase erbB-2; p185neu; CD340; Erbb2; Neu

    		 Cynomolgus HEK293
    Erb-b2 receptor tyrosine kinase 2 is a member of EGFR family. Erb-b2 receptor tyrosine kinase 2 is over-expressed in the tumors of many types of cancers. Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. HER2/CD340 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived HER2/CD340 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of HER2/CD340 Protein, Cynomolgus (HEK293, Fc) is 630 a.a., with molecular weight of ~96.4 kDa.
  • HY-P75805
    HER2/CD340 Protein, Cynomolgus (HEK293, His)

    Receptor TYRosine-protein kinase erbB-2; p185neu; CD340; Erbb2; Neu

    		 Cynomolgus HEK293
    Erb-b2 receptor tyrosine kinase 2 is a member of EGFR family. Erb-b2 receptor tyrosine kinase 2 is over-expressed in the tumors of many types of cancers. Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. HER2/CD340 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Cynomolgus (HEK293, His) is 630 a.a., with molecular weight of ~80-100 kDa.
  • HY-P70124
    CSF1R Protein, Cynomolgus (HEK293, His)

    rCynReceptor protein-TYRosine kinase/CSF1R, His; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS

    		 Cynomolgus HEK293
    CSF1R is colony-stimulating factor receptor, a type I transmembrane protein receptor. Binding of CSF1R to CSF-1 or IL-34 activates a cascade of extracellular pro-cell survival kinases, including PI3K, ERK1/2, and JNK. CSF1R also recruits multiple downstream effector proteins/pathways, including PI3K, Grb2, SFK, Src, PKC, etc. CSF1R is involved in embryonic development and tissue repair and is associated with tumorigenesis and cancer progression. CSF1R Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CSF1R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CSF1R Protein, Cynomolgus (HEK293, His) is 498 a.a., with molecular weight of 80-120 kDa.

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