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Results for "

( )-SHIN1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) ROS Kinase (1) SHMT (2)
By Research Areas:	Cancer (1) Infection (1)

4

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*SHIN1* Maximum Cited Publications 9 Publications Verification RZ-2994	SHMT	Cancer
SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC₅₀s of 5 and 13 nM, respectively, in an in vitro assay.

HY-112066B

(-)-SHIN1

1 Publications Verification

(-)-RZ-2994
Others Others

(-)-SHIN1 ((-)-RZ-2994) is an inactive (−) enantiomer of SHIN1 ^[1].
HY-112066A

(+)-SHIN1

1 Publications Verification

(+)-RZ-2994
SHMT Others

(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 ^[1].

HS-291	ROS Kinase Bacterial	Infection
HS-291 is a HtpG inhibitor of Borrelia burgdorferi (Bb). HS-291 contains BX-2819 (high affinity for Bb HtpG), PEG linker, and Verteporfin (HY-B0146) (a photoactive toxin).HS-291 produces reactive oxygen species under light activation to oxidize HtpG and a discrete protein subset near chaperone proteins and can quickly and irreversibly inactivate Bb ^[1].

Species:	Virus (2) Human (1)
Tag:	His (2) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	NS3 protease Protein, HCV (GST) Hepatitis C virus (HCV-1a) NS3 protease / helicase immunodominant region Protein ( GST)	Virus	E. coli
	NS3 protease Protein is a zinc-dependent serine protease. NS3 needs to bind to the viral protein NS4A to enable additional conformation changes that enhance activity and appropriate intracellular localization. NS3 protein induces Caspase-8-mediated apoptosis independently of its protease or helicase activity. NS3 protease Protein, HCV (GST) is the recombinant Virus-derived NS3 protease protein, expressed by E. coli , with N-GST labeled tag. The total length of NS3 protease Protein, HCV (GST) is 104 a.a., with molecular weight of ~37.9 kDa.

	VSTM2A Protein, Human ( E84K, HEK293, His) V-set and transmembrane domain-containing protein 2A; VSTM2	Human	HEK293
	VSTM2A Protein, a key player in early white and brown preadipocyte differentiation, actively promotes adipogenic commitment by upregulating the transcription factor PPARG. This regulatory role operates within a BMP4-dependent signaling pathway, highlighting intricate molecular mechanisms in differentiation. Additionally, VSTM2A functions as a homodimer, suggesting involvement in complex protein-protein interactions critical for its regulatory activities. VSTM2A Protein, Human ( E84K, HEK293, His) is the recombinant human-derived VSTM2A protein, expressed by HEK293 , with C-6*His labeled tag and E84K mutation. The total length of VSTM2A Protein, Human ( E84K, HEK293, His) is 220 a.a., with molecular weight of 38-40 kDa.

	HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) Influenza A H3N2 (A/Victoria/208/2009) Hemagglutinin / HA Protein (sf9, His)	Virus	Sf9 insect cells
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of HA/Hemagglutinin Protein, H3N2 ( EPI189220, sf9, His) is 530 a.a., with molecular weight of ~59.2 kDa.

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