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2'-​Deoxy-​2'-​fluoro-​5-​Methyluridine (Standard)

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Nom du produit Target Áreas de investigación Chemical Structure
  • HY-128710R
    2'-Fluorothymidine (Standard)

    2'-​Deoxy-​2'-​fluoro-​5-​Methyluridine (Standard)

    		 Reference Standards Nucleoside Antimetabolite/Analog Cancer
    2'-Fluorothymidine (Standard) is the analytical standard of 2'-Fluorothymidine. This product is intended for research and analytical applications. 2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine) is a nucleoside analog and hCNT inhibitor, with an IC50 of 1.1 μM against hCNT1 and an IC50 of 9.7 μM against hCNT3. 2'-Fluorothymidine undergoes phosphorylation by cytosolic thymidine kinase (TK1) and mitochondrial thymidine kinase (TK2). 2'-Fluorothymidine acts as a backbone stabilizer in oligonucleotide synthesis and can also form radiolabeled candidates. 2'-Fluorothymidine is applicable in tumor-related research.
    2'-Fluorothymidine (Standard)

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