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Results for "57653-26-6" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-101478

    mGluR Neurological Disease
    Fenobam is a selective, orally active, and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively). Fenobam displays inverse agonist activity which blocks the mGlu5 receptor basal activity with an IC50 of 84 nM. Fenobam exerts anxiolytic activity.