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ADT

" in MedChemExpress (MCE) Product Catalog:

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同位体標識化合物

製品番号 製品名 Target 研究分野 構造式
  • HY-109582
    ADT-OH
    4 Publications Verification

    5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1

    		 Apoptosis FAK Cancer
    ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases .
    ADT-OH
  • HY-157887
    ADT-007
    1 Publications Verification

    		 Ras Cancer
    ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes .
    ADT-007
  • HY-151027S
    Androsterone glucuronide-d4

    ADT-G-d4

    		 Isotope-Labeled Compounds Others
    Androsterone glucuronide-d4 is the deuterium labeled Androsterone glucuronide .
    Androsterone glucuronide-d4
  • HY-177106
    ADT-1004

    		Drug Intermediate Ras Cancer
    ADT-1004 is an orally active prodrug of ADT-007 (HY-157887). ADT-007 is a reversible, highly potent and selective pan-RAS inhibitor that binds to the nucleotide-free conformation of RAS proteins and blocks their GTP activation, thereby inhibiting the downstream MAPK and AKT signaling pathways. ADT-1004 can be used for the research of pancreatic ductal adenocarcinoma .
    ADT-1004
  • HY-106770
    Esuprone

    		Monoamine Oxidase Neurological Disease
    Esuprone is a brain-penetrant, orally active and selective MAO A inhibitor with an IC50 of 7.3 nM. Esuprone can be used for neurological research .
    Esuprone
  • HY-113104
    Androsterone glucuronide

    ADT-G

    		 Endogenous Metabolite Drug Metabolite Metabolic Disease
    Androsterone glucuronide (ADT-G) is one of the main metabolites of oral testosterone in humans and can be found in urine. The level of Androsterone glucuronide can reflect the absorption and hepatic metabolism of testosterone .
    Androsterone glucuronide
  • HY-109582R
    ADT-OH (Standard)

    5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione (Standard); ACS 1 (Standard)

    		 Apoptosis FAK Reference Standards Cancer
    ADT-OH (Standard) is the analytical standard of ADT-OH. This product is intended for research and analytical applications. ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases .
    ADT-OH (Standard)
  • HY-113104S
    Androsterone glucuronide-d4 sodium

    ADT-G-d4 sodium

    		 Isotope-Labeled Compounds Others
    Androsterone glucuronide-d4 (sodium) (ADT-G-d4 sodium) is the deuterium labeled Androsterone glucuronide sodium .
    Androsterone glucuronide-d4 sodium
  • HY-109582S
    ADT-OH-d4

    ACS 1-d4

    		 Isotope-Labeled Compounds FAK Apoptosis Cancer
    ADT-OH-d4 (ACS 1-d4) is the deuterium labeled ADT-OH (HY-109582). ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases .
    ADT-OH-d4

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