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Results for "

Aerosol flames Inhibitors

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156978

    Wy-48252

    Leukotriene Receptor Others
    Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD4 in guinea pigs, with an ID50 of 0.5mg/kg .
    Ritolukast
  • HY-127074

    HET acid

    Biochemical Assay Reagents Others
    Chlorendic acid (HET acid) can be used as a diacid component for the synthesis of oligoesters with potential flame retardant properties with aliphatic diols. Degradation by chlorine radicals may be responsible for the flame retardancy of HET acid-based oligoesters .
    Chlorendic acid
  • HY-W023144

    Tris(1-chloropropan-2-yl) phosphate

    Biochemical Assay Reagents Others
    Tris(1-chloro-2-propyl) phosphate is an orally active flame retardant .
    Tris(1-chloro-2-propyl) phosphate
  • HY-15929

    2,4,6-Tribromo-3-hydroxybenzoic acid

    Biochemical Assay Reagents Others
    TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H2O2) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .
    TBHBA
  • HY-108712
    TDCPP
    5+ Cited Publications

    Tris(1,3-dichloroisopropyl)phosphate

    Biochemical Assay Reagents Cancer
    TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.
    TDCPP
  • HY-W013058

    DBDPE; 1,2-Bis(perbromophenyl)ethane

    Biochemical Assay Reagents Neurological Disease Metabolic Disease
    Decabromodiphenyl ethane (DBDPE; 1,2-Bis(perbromophenyl)ethane) is a brominated flame retardant. Decabromodiphenyl ethane can exhibit neurotoxicity, thyroid toxicity, reproductive developmental toxicity, hepatotoxicity, and oxidative stress in living organisms .
    Decabromodiphenyl ethane
  • HY-D0077

    Oregon green 488

    Fluorescent Dye Others
    2',7'-Difluorofluorescein (Oregon green 488) can be used to measure the pH of aerosol particles in the range of 2-7 .
    2',7'-Difluorofluorescein
  • HY-129785

    Phosphodiesterase (PDE) Neurological Disease Inflammation/Immunology
    CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg) .
    CP-220629
  • HY-108712R

    Biochemical Assay Reagents Cancer
    TDCPP (Standard) is the analytical standard of TDCPP. This product is intended for research and analytical applications. TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.
    TDCPP (Standard)
  • HY-N2296

    Others Others
    (2R,3R)-3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant for transparent polycarbonate products or in elevator illumination devices research .
    (2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one
  • HY-W040186

    Biochemical Assay Reagents Others
    1-Naphthenyl phosphate hydrate sodium is commonly used as a flame retardant for various materials such as plastics, textiles, and construction materials. In addition, its potential use as a corrosion inhibitor and as an ingredient in fertilizers and detergents has been investigated. Its hydrated form contains variable amounts of water molecules, which affects its physical properties and applications.
    1-Naphthenyl phosphate hydrate sodium
  • HY-141728

    BCIPP

    Endogenous Metabolite Metabolic Disease
    Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .
    Bis(1-chloro-2-propyl) phosphate
  • HY-W008954

    Biochemical Assay Reagents Others
    Tris(2-ethylhexyl) phosphate is an organophosphorus flame retardant analog with considerable ecological toxicity. Tris(2-ethylhexyl) phosphate can be used as neutral carriers to make organic ammonium ion-selective membrane electrodes. Tris(2-ethylhexyl) phosphate is widely applied in furniture, textiles, building materials, electronics, and other chemicals .
    Tris(2-ethylhexyl) phosphate
  • HY-11098

    R170591

    RSV Infection
    JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg .
    JNJ 2408068
  • HY-Y1322

    Monoamine Oxidase Reactive Oxygen Species NF-κB Interleukin Related TNF Receptor Neurological Disease Inflammation/Immunology
    Triphenyl phosphate is an organic phosphate flame retardant. Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NFκB, leading to abnormal neurological behavior. Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NFκB), interleukin-6, and tumor necrosis factor α. Triphenyl phosphate can also cause allergic contact dermatitis .
    Triphenyl phosphate
  • HY-W105318

    PBP

    TGF-beta/Smad Apoptosis Cancer
    Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .
    Pentabromophenol
  • HY-W009066

    EHDPP; Octicizer

    PPAR Progesterone Receptor Estrogen Receptor/ERR Endocrinology
    2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC20: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC50: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, human chorionic gonadotropin (hCG) and progesterone secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development .
    2-Ethylhexyl diphenyl phosphate
  • HY-115314

    LG 30435

    Histamine Receptor Inflammation/Immunology
    Mequitamium iodide (LG 30435) is an antihistamine drug with antiallergic and bronchodilatory activity. Mequitamium iodide can effectively antagonize airway contraction and inflammatory responses induced by histamine and antigens. Mequitamium iodide has nanomolar affinity for the H1 and smooth muscle receptors of histamine and mequitin. Mequitamium iodide, when administered in aerosol form, significantly inhibits histamine- and antigen-induced increases in airway pressure in allergic mice. Mequitamium iodide reduces antigen-induced eosinophil accumulation in the airways. Mequitamium iodide also exhibits inhibitory effects on PAF-induced platelet aggregation and bronchoconstriction, and can be used in the study of allergic diseases such as rhinitis and asthma .
    Mequitamium iodide
  • HY-108858
    Dornase alfa
    1 Publications Verification

    rhDNase

    DNA/RNA Synthesis Endonuclease Inflammation/Immunology
    Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus, reduces sputum viscosity, thereby improving mucus clearance efficiency, reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF), reduce the risk of acute pulmonary exacerbations, and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation, specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms .
    Dornase alfa
  • HY-W653929

    BCIPP-d12

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .
    Bis(1-chloro-2-propyl) phosphate-d12

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