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Aerosol flames Inhibitors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Biochemical Assay Reagents (8) DNA/RNA Synthesis (1) Endogenous Metabolite (2) Endonuclease (1) Estrogen Receptor/ERR (1) Fluorescent Dye (1) Histamine Receptor (1) Interleukin Related (1) Isotope-Labeled Compounds (1) Leukotriene Receptor (1) Monoamine Oxidase (1) NF-κB (1) Phosphodiesterase (PDE) (1) PPAR (1) Progesterone Receptor (1) Reactive Oxygen Species (1) RSV (1) TGF-beta/Smad (1) TNF Receptor (1)
By Research Areas:	Cancer (3) Endocrinology (1) Infection (1) Inflammation/Immunology (4) Metabolic Disease (3) Neurological Disease (3)

By Targets:

Apoptosis (1)

Biochemical Assay Reagents (8)

DNA/RNA Synthesis (1)

Endogenous Metabolite (2)

Endonuclease (1)

Estrogen Receptor/ERR (1)

Fluorescent Dye (1)

Histamine Receptor (1)

Interleukin Related (1)

Isotope-Labeled Compounds (1)

Leukotriene Receptor (1)

Monoamine Oxidase (1)

NF-κB (1)

Phosphodiesterase (PDE) (1)

PPAR (1)

Progesterone Receptor (1)

Reactive Oxygen Species (1)

RSV (1)

TGF-beta/Smad (1)

TNF Receptor (1)

By Research Areas:

Cancer (3)

Endocrinology (1)

Infection (1)

Inflammation/Immunology (4)

Metabolic Disease (3)

Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Serpin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-156978

Ritolukast Wy-48252	Leukotriene Receptor	Others
Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD₄/E₄) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD₄ in guinea pigs, with an ID₅₀ of 0.5mg/kg .

HY-127074

Chlorendic acid HET acid	Biochemical Assay Reagents	Others
Chlorendic acid (HET acid) can be used as a diacid component for the synthesis of oligoesters with potential flame retardant properties with aliphatic diols. Degradation by chlorine radicals may be responsible for the flame retardancy of HET acid-based oligoesters .

HY-W023144

Tris(1-chloro-2-propyl) phosphate Tris(1-chloropropan-2-yl) phosphate	Biochemical Assay Reagents	Others
Tris(1-chloro-2-propyl) phosphate is an orally active flame retardant .

HY-15929

TBHBA 2,4,6-Tribromo-3-hydroxybenzoic acid	Biochemical Assay Reagents	Others
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H₂O₂) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .

HY-108712

TDCPP 5+ Cited Publications Tris(1,3-dichloroisopropyl)phosphate	Biochemical Assay Reagents	Cancer
TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.

HY-W013058

Decabromodiphenyl ethane DBDPE; 1,2-Bis(perbromophenyl)ethane	Biochemical Assay Reagents	Neurological Disease Metabolic Disease
Decabromodiphenyl ethane (DBDPE; 1,2-Bis(perbromophenyl)ethane) is a brominated flame retardant. Decabromodiphenyl ethane can exhibit neurotoxicity, thyroid toxicity, reproductive developmental toxicity, hepatotoxicity, and oxidative stress in living organisms .

HY-D0077

2',7'-Difluorofluorescein Oregon green 488	Fluorescent Dye	Others
2',7'-Difluorofluorescein (Oregon green 488) can be used to measure the pH of aerosol particles in the range of 2-7 .

HY-129785

CP-220629	Phosphodiesterase (PDE)	Neurological Disease Inflammation/Immunology
CP-220629 is a potent inhibitor of PDE4, with the IC₅₀ of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED₅₀ 2.0 mg/kg) .

HY-108712R

TDCPP (Standard)	Biochemical Assay Reagents	Cancer
TDCPP (Standard) is the analytical standard of TDCPP. This product is intended for research and analytical applications. TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.

HY-N2296

(2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one	Others	Others
(2R,3R)-3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant for transparent polycarbonate products or in elevator illumination devices research .

HY-W040186

1-Naphthenyl phosphate hydrate sodium	Biochemical Assay Reagents	Others
1-Naphthenyl phosphate hydrate sodium is commonly used as a flame retardant for various materials such as plastics, textiles, and construction materials. In addition, its potential use as a corrosion inhibitor and as an ingredient in fertilizers and detergents has been investigated. Its hydrated form contains variable amounts of water molecules, which affects its physical properties and applications.

HY-141728

Bis(1-chloro-2-propyl) phosphate BCIPP	Endogenous Metabolite	Metabolic Disease
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

HY-W008954

Tris(2-ethylhexyl) phosphate	Biochemical Assay Reagents	Others
Tris(2-ethylhexyl) phosphate is an organophosphorus flame retardant analog with considerable ecological toxicity. Tris(2-ethylhexyl) phosphate can be used as neutral carriers to make organic ammonium ion-selective membrane electrodes. Tris(2-ethylhexyl) phosphate is widely applied in furniture, textiles, building materials, electronics, and other chemicals .

HY-11098

JNJ 2408068 R170591	RSV	Infection
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg .

HY-Y1322

Triphenyl phosphate	Monoamine Oxidase Reactive Oxygen Species NF-κB Interleukin Related TNF Receptor	Neurological Disease Inflammation/Immunology
Triphenyl phosphate is an organic phosphate flame retardant. Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NFκB, leading to abnormal neurological behavior. Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NFκB), interleukin-6, and tumor necrosis factor α. Triphenyl phosphate can also cause allergic contact dermatitis .

HY-W105318

Pentabromophenol PBP	TGF-beta/Smad Apoptosis	Cancer
Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .

HY-W009066

2-Ethylhexyl diphenyl phosphate EHDPP; Octicizer	PPAR Progesterone Receptor Estrogen Receptor/ERR	Endocrinology
2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC₂₀: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC₅₀: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, human chorionic gonadotropin (hCG) and progesterone secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development .

HY-115314

Mequitamium iodide LG 30435	Histamine Receptor	Inflammation/Immunology
Mequitamium iodide (LG 30435) is an antihistamine drug with antiallergic and bronchodilatory activity. Mequitamium iodide can effectively antagonize airway contraction and inflammatory responses induced by histamine and antigens. Mequitamium iodide has nanomolar affinity for the H1 and smooth muscle receptors of histamine and mequitin. Mequitamium iodide, when administered in aerosol form, significantly inhibits histamine- and antigen-induced increases in airway pressure in allergic mice. Mequitamium iodide reduces antigen-induced eosinophil accumulation in the airways. Mequitamium iodide also exhibits inhibitory effects on PAF-induced platelet aggregation and bronchoconstriction, and can be used in the study of allergic diseases such as rhinitis and asthma .

HY-108858

Dornase alfa 1 Publications Verification rhDNase	DNA/RNA Synthesis Endonuclease	Inflammation/Immunology
Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus, reduces sputum viscosity, thereby improving mucus clearance efficiency, reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF), reduce the risk of acute pulmonary exacerbations, and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation, specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms .

HY-W653929

Bis(1-chloro-2-propyl) phosphate-d12 BCIPP-d₁₂	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Bis(1-chloro-2-propyl) phosphate-d₁₂ is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

Cat. No.	Product Name	Type

HY-15929

TBHBA 2,4,6-Tribromo-3-hydroxybenzoic acid	Biochemical Assay Reagents
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H₂O₂) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .

TBHBA

2,4,6-Tribromo-3-hydroxybenzoic acid

Biochemical Assay Reagents

TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H₂O₂) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .

HY-W040186

1-Naphthenyl phosphate hydrate sodium	Biochemical Assay Reagents
1-Naphthenyl phosphate hydrate sodium is commonly used as a flame retardant for various materials such as plastics, textiles, and construction materials. In addition, its potential use as a corrosion inhibitor and as an ingredient in fertilizers and detergents has been investigated. Its hydrated form contains variable amounts of water molecules, which affects its physical properties and applications.

1-Naphthenyl phosphate hydrate sodium

Biochemical Assay Reagents

1-Naphthenyl phosphate hydrate sodium is commonly used as a flame retardant for various materials such as plastics, textiles, and construction materials. In addition, its potential use as a corrosion inhibitor and as an ingredient in fertilizers and detergents has been investigated. Its hydrated form contains variable amounts of water molecules, which affects its physical properties and applications.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-141728

Bis(1-chloro-2-propyl) phosphate BCIPP	Structural Classification Natural Products Source classification Disease markers Endogenous metabolite	Endogenous Metabolite
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

HY-N2296

(2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one	Flavanonols Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Sophora flavescens Aiton Plants Disease Research Fields	Others
(2R,3R)-3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant for transparent polycarbonate products or in elevator illumination devices research .

Cat. No.	Product Name	Chemical Structure

HY-W653929

Bis(1-chloro-2-propyl) phosphate-d12
Bis(1-chloro-2-propyl) phosphate-d₁₂ is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

Bis(1-chloro-2-propyl) phosphate-d12

Bis(1-chloro-2-propyl) phosphate-d₁₂ is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

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Aerosol flames Inhibitors

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products