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Results for "

BMP9

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

1

Inhibitory Antibodies

3

Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P700530

    GDF-2; BMP-9; GDF2; BMP9

    Human P. pastoris
    BMP-9/GDF-2 Protein, a robust angiogenesis inhibitor, selectively signals through ACVRL1 in endothelial cells. Its signaling pathway requires the TGF-beta coreceptor endoglin/ENG for efficient activation of SMAD1. Existing as a homodimer with disulfide-linked structures, the protein forms complexes with ACVRL1, BMPR2, and ACVR2B, crucial for signal transduction. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1. Notably, it interacts with the type I receptor ACVR1, contributing to the intricate regulatory network in the TGF-beta signaling pathway. GDF-2 Protein, Human (P. pastoris, His) is the recombinant human-derived GDF-2 protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of GDF-2 Protein, Human (P. pastoris, His) is 130 a.a., with molecular weight of 16.3 kDa.
  • HY-P700033AF

    GDF-2; BMP-9; GDF2; BMP9

    Human E. coli
    BMP-9/GDF-2 Protein, a robust angiogenesis inhibitor, selectively signals through ACVRL1 in endothelial cells. Its signaling pathway requires the TGF-beta coreceptor endoglin/ENG for efficient activation of SMAD1. Existing as a homodimer with disulfide-linked structures, the protein forms complexes with ACVRL1, BMPR2, and ACVR2B, crucial for signal transduction. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1. Notably, it interacts with the type I receptor ACVR1, contributing to the intricate regulatory network in the TGF-beta signaling pathway. Animal-Free BMP-9/GDF-2 Protein, Human (His) is the recombinant human-derived animal-FreeBMP-9/GDF-2 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free BMP-9/GDF-2 Protein, Human (His) is 110 a.a., with molecular weight of ~12.89 kDa.
  • HY-P77580

    GDF-2; BMP-9; GDF2; BMP9

    Mouse HEK293
    The BMP-9/GDF-2 protein is a potent inhibitor of angiogenesis that signals through AVRL1, and endoglin/ENG is required for SMAD1 signaling in endothelial cells. As a homodimer with a disulfide-linked structure, BMP-9/GDF-2 forms a complex with AVRL1, BMPR2, and ACVR2B, which is critical for its signaling cascade. BMP-9/GDF-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived BMP-9/GDF-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BMP-9/GDF-2 Protein, Mouse (HEK293, Fc) is 110 a.a., with molecular weight of 47-50 kDa.

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