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BMX+Kinase

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-80002
    BMX-IN-1
    5+ Cited Publications

    BMX kinase inhibitor

    		 Btk BMX Kinase Cancer
    BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys 496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
    BMX-IN-1
  • HY-101267
    CHMFL-BMX-078
    3 Publications Verification

    CHMFL-BMX 078

    		 BMX Kinase Cancer
    CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.
    CHMFL-BMX-078
  • HY-174142
    IHMT-15130

    		BMX Kinase Cardiovascular Disease Inflammation/Immunology
    IHMT-15130 is a highly potent irreversible BMX kinase inhibitor (IC50=1.47 nM). IHMT-15130 inhibits the secretion of inflammatory cytokines, blocks inflammatory signaling pathways, and alleviates Angiotensin II-induced myocardial hypertrophy in mice. IHMT-15130 is promising for research of myocardial hypertrophy .
    IHMT-15130
  • HY-101267R
    CHMFL-BMX-078 (Standard)

    CHMFL-BMX 078 (Standard)

    		 BMX Kinase Reference Standards Cancer
    CHMFL-BMX-078 (Standard) is the analytical standard of CHMFL-BMX-078 (HY-101267). This product is intended for research and analytical applications. CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.
    CHMFL-BMX-078 (Standard)

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