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CD300LF

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Cat. No. Compare Product Name Species Source
  • HY-P71561
    CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO)

    CD300LF; Clm1CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; CD antigen CD300f

    		 Rat E. coli
    CMRF35-like molecule 1 (CLM-1) Protein serves as an inhibitory receptor for myeloid and mast cells, crucial in immune homeostasis by regulating various immune responses. CLM-1 positively modulates macrophage-mediated efferocytosis by recognizing phosphatidylserine on apoptotic cells. It inhibits dendritic cell-mediated efferocytosis and Fc epsilon receptor-dependent mast cell activation. CLM-1 may act as a coreceptor for IL-4, enhancing IL-4- and IL-13-induced signaling. Additionally, it negatively regulates TLR signaling and inhibits osteoclast formation while inducing macrophage cell death. The protein interacts with PTPN6/SHP-1 and associates with IL4R. CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO) is the recombinant rat-derived CMRF35-like molecule 1 protein, expressed by E. coli, with N-His, C-Myc, N-SUMO labeled tag. The total length of CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO) is 163 a.a., with molecular weight of ~38.3 kDa.

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