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CSI

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122228
    Cestrin

    		Cellulose Synthase Others
    Cestrin is a cellulose Synthase 1 (CESA1) inhibitor. Cestrin inhibits cell elongation and reduces cellulose content and interferes with the trafficking of cellulose synthase complexes and their associated proteins KORRIGAN1 and POM2/CSI1 .
    Cestrin
  • HY-169379
    CSI118 TFA

    		Ligands for Target Protein for PROTAC Cancer
    CSI118 TFA (Compound 1) is a Ligand for Target Protein for PROTAC. CSI118 TFA can be used to synthesize CSI86 (HY-169378) .
    CSI118 TFA
  • HY-169378
    CSI86

    		PROTACs c-Myc Cancer
    CSI86 is a MYC-targeting PROTAC degrader with antiproliferative activity (IC50: 13-18 μM) . CSI86 is composed of MYC inhibitor (red part) CSI118 TFA (HY-169379), E3 ligase ligand (blue part) VH032 (HY-120217), and PROTAC linker (black part) Succinic anhydride (HY-79369). The conjugate composed of E3 ligase ligand and linker is (S,R,S)-CO-C2-acid (HY-131866).
    CSI86
  • HY-168695
    BRD9 ligand-7

    		Ligands for Target Protein for PROTAC Cancer
    BRD9 ligand-7 is a Ligand for Target Protein for PROTAC. CSI118 TFA can be used to synthesize BRD9 Degrader-1 (HY-156401) .
    BRD9 ligand-7

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