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CXCL10

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  • HY-P7227
    IP-10/CRG-2/CXCL10 Protein, Mouse

    rMuIP-10/CXCL10; C-X-C motif chemokine 10; Gamma-IP10; Mob-1

    		 Mouse E. coli
    CXCL10, also known as interferon γ-induced protein 10 kDa (IP-10), is a cytokine belonging to the CXC chemokine family. CXCL10 exerts its biological effects by binding to CXCR3. CXCL10 is a pleiotropic molecule capable of exerting potent biological functions, including promoting the chemotactic activity of CXCR3+ cells, inducing apoptosis, regulating cell growth and proliferation as well as angiogenesis in infectious and inflammatory diseases and cancer. IP-10/CRG-2/CXCL10 Protein, Mouse consists of 77 amino acids (I22-P98) and is expressed in E. coli.
  • HY-P700168AF
    Animal-Free IP-10/CRG-2/CXCL10 Protein, Mouse (His)

    IP-10; Gamma-Interferon Inducible Protein 10; Crg-2

    		 Mouse E. coli
    The IP-10/CRG-2/CXCL10 Protein, a pro-inflammatory cytokine, modulates immune cells, cell growth, apoptosis, and angiostatic effects. Crucial during viral infections, it activates and migrates immune cells to infected sites by binding to CXCR3. Mechanistically, it triggers G protein-mediated signaling, activating the phospholipase C-dependent pathway, increasing intracellular calcium, and reorganizing actin. This axis also aids neuronal response to brain injury by activating microglia. The IP-10/CRG-2/CXCL10 Protein can exist as a monomer, dimer, or tetramer and interacts with the CXCR3 receptor. Animal-Free IP-10/CRG-2/CXCL10 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIP-10/CRG-2/CXCL10 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free IP-10/CRG-2/CXCL10 Protein, Mouse (His) is 77 a.a., with molecular weight of ~9.47 kDa.

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