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Isoforms Recommended: DCAMKL
Results for "

DCAMKL3

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-186224
    GW296115

    		PDGFR DAPK ULK p62 Autophagy Apoptosis Cancer
    GW296115 is a multi-target inhibitor with the following IC50 values against its targets: 8.4 nM for BRSK2, 21 nM for BRSK1, 1.8 μM for PDGFRβ, 5.5 nM for STK17B/DRAK2, 28 nM for DRAK1, 20 nM for PHKG1, and 89 nM for DCAMKL3. GW296115 downregulates the phosphorylation of S317 site on ULK1 and S351 site on P62, which are AMPK substrates driven by BRSK2. GW296115 does not alter the phosphorylation level of AMPK at T172, reduces nutrient deprivation-mediated Autophagy and autophagosome formation, and enhances Apoptosis. GW296115 exhibits anticancer activity against triple-negative breast cancer. GW296115 is applicable for breast cancer-related research .
    GW296115
  • HY-RS03580
    DCLK3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    DCLK3 Human Pre-designed siRNA Set A contains three designed siRNAs for DCLK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DCLK3 Human Pre-designed siRNA Set A
    DCLK3 Human Pre-designed siRNA Set A

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