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ERAP1-IN-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-133125
    ERAP1-IN-1
    5 Publications Verification

    		 Aminopeptidase Inflammation/Immunology
    ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates .
    ERAP1-IN-1
  • HY-169913
    ERAP1 modulator-1

    		Aminopeptidase Inflammation/Immunology Cancer
    ERAP1 modulator-1 (Compound 1) is the modulator for endoplasmic reticulum aminopeptidase 1 (ERAP1) with IC50 < 250 nM .
    ERAP1 modulator-1
  • HY-183267
    ERAP1-IN-4

    		Aminopeptidase Cancer
    ERAP1-IN-4 is an orally acvtive endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor with a pIC50 of 7.9 and an LLE of 5.3. ERAP1-IN-4 inhibits hydrolysis of peptide substrates by ERAP1, with high activity against Allotype1 and Allotype2. ERAP1-IN-4 reduced efficacy against other allotypes, and modulates ERAP1-mediated peptide processing to inhibit antigenic epitope presentation. ERAP1-IN-4 can be used for the research of cancer[1].
    ERAP1-IN-4

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