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Results for "

FSHR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Estrogen Receptor/ERR (2) GnRH Receptor (1) Small Interfering RNA (siRNA) (1) TSH Receptor (1)
By Research Areas:	Cancer (1) Endocrinology (3)

5

Inhibitors & Agonists

2

Peptides

1

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

FSHR agonist 1	Estrogen Receptor/ERR	Endocrinology
FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC₅₀ of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR .

hFSH-β-(33-53) (TFA)	Estrogen Receptor/ERR	Cancer
hFSH-β-(33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a *FSHR* (follicle-stimulating hormone receptor) antagonist. hFSH-β-(33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells .

ML224 1 Publications Verification NCGC00242364; ANTAG3	TSH Receptor	Endocrinology
ML224 (NCGC00242364) is a selective TSHR antagonist with an IC₅₀ value of 2.1 µM. ML224 can be used in the study of Graves' disease and other thyroid disorders.

FSHR Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FSHR Human Pre-designed siRNA Set A contains three designed siRNAs for FSHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FSHR Human Pre-designed siRNA Set A FSHR Human Pre-designed siRNA Set A

Fsh receptor-binding inhibitor fragment(bi-10)	GnRH Receptor	Endocrinology
FSH receptor-binding inhibitor fragment(bi-10) is a potent FSH antagonist. FSH receptor-binding inhibitor fragment(bi-10) blocks the binding of FSH to FSHR, and alteres FSH action at the receptor level. FSH receptor-binding inhibitor fragment(bi-10) results in the suppression of ovulation and causes follicular atresia of mice. FSH receptor-binding inhibitor fragment(bi-10) has the potential for utilizing to restrain the carcinogenesis of ovarian cancer by down-regulating overexpression of FSHR and ERβ in the ovaries .

Cat. No.	Product Name	Target	Research Area

hFSH-β-(33-53) (TFA)	Estrogen Receptor/ERR	Cancer
hFSH-β-(33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a *FSHR* (follicle-stimulating hormone receptor) antagonist. hFSH-β-(33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells .

Fsh receptor-binding inhibitor fragment(bi-10)	GnRH Receptor	Endocrinology
FSH receptor-binding inhibitor fragment(bi-10) is a potent FSH antagonist. FSH receptor-binding inhibitor fragment(bi-10) blocks the binding of FSH to FSHR, and alteres FSH action at the receptor level. FSH receptor-binding inhibitor fragment(bi-10) results in the suppression of ovulation and causes follicular atresia of mice. FSH receptor-binding inhibitor fragment(bi-10) has the potential for utilizing to restrain the carcinogenesis of ovarian cancer by down-regulating overexpression of FSHR and ERβ in the ovaries .

Cat. No.	Compare	Product Name	Species	Source

	FSHR Protein, Human (His) Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; FSHR; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1	Human	E. coli
	FSHR, a G protein-coupled receptor, specifically recognizes follitropin (FSH) and activates PI3K-AKT and ERK1/ERK2 pathways by promoting cAMP production. Operating as a homotrimer, FSHR binds the heterodimeric FSH hormone, forming a functional unit for signal transduction. Its regulatory mechanisms involve interaction with ARRB2, and independently of FSH stimulation, it engages with APPL2, demonstrating versatility in diverse cellular contexts. FSHR Protein, Human (His) is the recombinant human-derived FSHR protein, expressed by E. coli , with N-6*His labeled tag. The total length of FSHR Protein, Human (His) is 349 a.a., with molecular weight of 47-51 kDa.

Cat. No.	Product Name	Application	Reactivity

FSH receptor Antibody Follicle-stimulating hormone receptor precursor; Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follitropin receptor; FSHRO; LGR1; ODG1; Follicle-stimulating hormone receptor; FSH-R; FSH R; FSHR; FSHR_HUMAN; MGC141667; MGC141668; ovarian dysgenesis 1.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Dog, Pig, Cow, Horse, Sheep, Guinea Pig)
FSH receptor Antibody is an unconjugated, approximately 78 kDa, rabbit-derived, anti-FSH receptor polyclonal antibody. FSH receptor Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, sheep, guinea pig background without labeling.

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