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Results for "

FXIIa

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99631
    Garadacimab
    1 Publications Verification

    CSL312

    		 Factor Xa Cardiovascular Disease
    Garadacimab (CSL312) is a first-in-class, fully human IgG4 monoclonal antibody targeting activated factor XII (FXIIa). Garadacimab has the potential for hereditary angioedema research .
    Garadacimab
  • HY-163348
    FXIIa-IN-4

    		Factor Xa Thrombin Cardiovascular Disease
    FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, ＞50 μM for FXIIa, thrombin and FXIa, respectively. FXIIa-IN-4 can be used for study of anticoagulant .
    <em>FXIIa</em>-IN-4
  • HY-163347
    FXIIa-IN-3

    		Others Cardiovascular Disease
    FXIIa-IN-3 (Compound 8) is a potent and selective Factor XIIa (FXIIa) inhibitor, with an IC50 of 0.045 μM. FXIIa-IN-3 also exhibits a substantial margin of selectivity against related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 can be used for the research of thromboembolic diseases .
    <em>FXIIa</em>-IN-3
  • HY-149397
    FXIIa-IN-2

    		Others Cardiovascular Disease
    FXIIa-IN-1-IN-2 (Compound 21) is a Factor XIIa inhibitor (Ki app: 62.2 nM). FXIIa-IN-1-IN-2 can be used for research of thrombosis .
    <em>FXIIa</em>-IN-2
  • HY-149396
    FXIIa-IN-1

    		Others Cardiovascular Disease
    XIIa-IN-1-IN-3 (Compound 22) is a Factor XIIa inhibitor (Ki app: 97.8 nM). XIIa-IN-1-IN-3 can be used for research of thrombosis .
    <em>FXIIa</em>-IN-1
  • HY-P99415
    Abelacimab

    MAA868

    		 Factor Xa Cardiovascular Disease
    Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies .
    Abelacimab
  • HY-152150
    Thrombin inhibitor 7

    		Others Metabolic Disease
    Thrombin inhibitor 7 is a potent FXIIa inhibitor with IC50 values of 28 nM, >132 µM for FXIIa and FXIa, respectively. Thrombin inhibitor 7 shows low cytotoxicity .
    Thrombin inhibitor 7

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