FXIIa-IN-4
Based on 1 publication(s) in Google Scholar
FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, ＞50 μM for FXIIa, thrombin and FXIa, respectively. FXIIa-IN-4 can be used for study of anticoagulant.
For research use only. We do not sell to patients.
- Purity: 98.87%
- Formula: C11H9FN4O3
- Molecular Weight:264.21
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Metabolism/Protease Compound Library
HY-L012
-
Anti-Cardiovascular Disease Compound Library
HY-L046
-
Coagulation and Anti-coagulation Compound Library
HY-L136
-
Metabolic Enzyme Compound Library
HY-L146
-
Protease Inhibitor Library
HY-L147
-
Highly Selective Inhibitors Library
HY-L158
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
Publications Citing Use of MedChemExpress (MCE) FXIIa-IN-4
More
Biological Activity
Chemical Information
-
Appearance Solid
-
Molecular Weight 264.21
-
Formula C11H9FN4O3
-
Color White to off-white
-
SMILES
O=C(C1=NN(C(C2=CC=C(F)C=C2)=O)C(N)=N1)OC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Cell Mol Biol (Noisy-le-grand)
Multidimensional assessment of natural ligands fisetin, morin and rutin against factor XIIa activity using in vitro and in silico studies. [Abstract]2025 Dec 28;71(12):72-80. PMID: 41456261
Solvent & Solubility
DMSO : 25 mg/mL (94.62 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7849 mL | 18.9243 mL | 37.8487 mL | 94.6217 mL |
| 5 mM | 0.7570 mL | 3.7849 mL | 7.5697 mL | 18.9243 mL | |
| 10 mM | 0.3785 mL | 1.8924 mL | 3.7849 mL | 9.4622 mL | |
| 15 mM | 0.2523 mL | 1.2616 mL | 2.5232 mL | 6.3081 mL | |
| 20 mM | 0.1892 mL | 0.9462 mL | 1.8924 mL | 4.7311 mL | |
| 25 mM | 0.1514 mL | 0.7570 mL | 1.5139 mL | 3.7849 mL | |
| 30 mM | 0.1262 mL | 0.6308 mL | 1.2616 mL | 3.1541 mL | |
| 40 mM | 0.0946 mL | 0.4731 mL | 0.9462 mL | 2.3655 mL | |
| 50 mM | 0.0757 mL | 0.3785 mL | 0.7570 mL | 1.8924 mL | |
| 60 mM | 0.0631 mL | 0.3154 mL | 0.6308 mL | 1.5770 mL | |
| 80 mM | 0.0473 mL | 0.2366 mL | 0.4731 mL | 1.1828 mL |
FXIIa-IN-4 Related Classifications
HY-163348 Related Classifications
Powered by Bioz