FXIIa-IN-4
Based on 1 publication(s) in Google Scholar
FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, ＞50 μM for FXIIa, thrombin and FXIa, respectively. FXIIa-IN-4 can be used for study of anticoagulant.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.87%
- Fòrmula: C11H9FN4O3
- Peso molecular:264.21
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) FXIIa-IN-4
More
Actividad biológica
Descripciòn
Chemical Information
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Appearance Solid
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Peso molecular 264.21
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Fòrmula C11H9FN4O3
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Color White to off-white
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SMILES
O=C(C1=NN(C(C2=CC=C(F)C=C2)=O)C(N)=N1)OC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Mol Biol (Noisy-le-grand)
Multidimensional assessment of natural ligands fisetin, morin and rutin against factor XIIa activity using in vitro and in silico studies. [Abstract]2025 Dec 28;71(12):72-80. PMID: 41456261
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (94.62 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7849 mL | 18.9243 mL | 37.8487 mL | 94.6217 mL |
| 5 mM | 0.7570 mL | 3.7849 mL | 7.5697 mL | 18.9243 mL | |
| 10 mM | 0.3785 mL | 1.8924 mL | 3.7849 mL | 9.4622 mL | |
| 15 mM | 0.2523 mL | 1.2616 mL | 2.5232 mL | 6.3081 mL | |
| 20 mM | 0.1892 mL | 0.9462 mL | 1.8924 mL | 4.7311 mL | |
| 25 mM | 0.1514 mL | 0.7570 mL | 1.5139 mL | 3.7849 mL | |
| 30 mM | 0.1262 mL | 0.6308 mL | 1.2616 mL | 3.1541 mL | |
| 40 mM | 0.0946 mL | 0.4731 mL | 0.9462 mL | 2.3655 mL | |
| 50 mM | 0.0757 mL | 0.3785 mL | 0.7570 mL | 1.8924 mL | |
| 60 mM | 0.0631 mL | 0.3154 mL | 0.6308 mL | 1.5770 mL | |
| 80 mM | 0.0473 mL | 0.2366 mL | 0.4731 mL | 1.1828 mL |
FXIIa-IN-4 Related Classifications
HY-163348 Related Classifications
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