FXIIa-IN-3
FXIIa-IN-3 (Compound 8) is a potent and selective Factor XIIa (FXIIa) inhibitor, with an IC50 of 0.045 μM. FXIIa-IN-3 also exhibits a substantial margin of selectivity against related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 can be used for the research of thromboembolic diseases.
For research use only. We do not sell to patients.
- Formula: C14H16N4O6
- Molecular Weight:336.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
0.045 μM (FXIIa), 14.9 μM (FXIa), 47.6 μM (FXa), 0.019 μM (Thrombin)[1]
Chemical Information
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Molecular Weight 336.30
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Formula C14H16N4O6
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SMILES
O=C(C1=NN(C(C2=CC(OC)=C(OC)C(OC)=C2)=O)C(N)=N1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)