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GM1 (d18:1/C18:0)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) Endogenous Metabolite (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (1) Neurological Disease (1)

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Natural
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Isotope-Labeled Compounds

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-N15820

C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0)	Biochemical Assay Reagents	Others
C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) is a ganglioside.

HY-N16029

C18:0 Fuc-GM1 Ceramide (d18:1/18:0)	Biochemical Assay Reagents	Cancer
C18:0 Fuc-GM1 Ceramide (d18:1/18:0) is a ganglioside that can be used to synthesize lipid nanoparticles for drug delivery .

HY-167599S

C18:0-d7 Fuc-GM1 Ceramide (d18:1/18:0-d7)	Isotope-Labeled Compounds	Others
C18:0-d₇ Fuc-GM1 Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 Fuc-GM1 Ceramide (d18:1/18:0) .

HY-171936

Ganglioside GM1 ammonium GM1 (d18:1/C18:0) ammonium; C18 Ganglioside GM1 (d18:1/18:0) ammonium	Endogenous Metabolite	Neurological Disease
Ganglioside GM1 (ammonium) is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. Ganglioside GM1 (ammonium) is one of the most abundant gangliosides in the brain which provides neuroprotection. Ganglioside GM1 (ammonium) exhibits anti-inflammatory property. Ganglioside GM1 (ammonium) has a well-balanced amphiphilic behavior. Ganglioside GM1 (ammonium) can reduce the fluidity of the plasma membrane that implies a retention and enrichment of the ganglioside in specific membrane domains that are called lipid rafts. Ganglioside GM1 (ammonium) can modify the process of differentiation, amplifies responses to neurotrophic factors, protects against excitatory amino acid-related neurotoxicity. Ganglioside GM1 (ammonium) can alleviate acute nerve cell damage through blocking cytotoxicity and potentiating neurotophic factors. Ganglioside GM1 (ammonium) can be studied in neurodegenerative diseases such as Alzheimer’s disease .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N15820

C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0)	Lipid	Biochemical Assay Reagents
C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) is a ganglioside.

HY-N16029

C18:0 Fuc-GM1 Ceramide (d18:1/18:0)	Lipid	Biochemical Assay Reagents
C18:0 Fuc-GM1 Ceramide (d18:1/18:0) is a ganglioside that can be used to synthesize lipid nanoparticles for drug delivery .

Cat. No.	상품명	Chemical Structure

HY-167599S

C18:0-d7 Fuc-GM1 Ceramide (d18:1/18:0-d7)
C18:0-d₇ Fuc-GM1 Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 Fuc-GM1 Ceramide (d18:1/18:0) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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GM1 (d18:1/C18:0)

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products