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Results for "

Guanabenz

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12724A

    Parasite Adrenergic Receptor Cardiovascular Disease
    Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist. Guanabenz hydrochloride has antihypertensive effect and antiparasitic activity. Guanabenz hydrochloride interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz hydrochloride also is used for the research of high blood pressure .
    <em>Guanabenz</em> hydrochloride
  • HY-B0566
    Guanabenz Acetate
    2 Publications Verification

    BR-750; Wy8678 acetate

    Adrenergic Receptor Cardiovascular Disease Endocrinology
    Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
    <em>Guanabenz</em> Acetate
  • HY-111022

    Sephin1; IFB-088

    Phosphatase Infection Inflammation/Immunology
    Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect .
    Icerguastat
  • HY-12724

    Adrenergic Receptor Parasite Cardiovascular Disease
    Guanabenz is an orally active α-2-adrenoceptor agonist. Guanabenz has antihypertensive effect and antiparasitic activity. Guanabenz interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz also is used for the research of high blood pressure .
    <em>Guanabenz</em>
  • HY-W263279

    (E)-Wy-8678

    Adrenergic Receptor Cardiovascular Disease Neurological Disease
    (E)-Guanabenz ((E)-Wy-8678) is an orally active central α2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity, acts via stimulating central α2-adrenoceptors, and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34, and has neuroprotective activity. (E)-Guanabenz can be used for researching hypertension and Parkinson disease .
    (E)-<em>Guanabenz</em>
  • HY-110365

    Sephin1 Carbonate; IFB-088 Carbonate

    Phosphatase Infection
    Icerguastat (Sephin1) Carbonate, a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat Carbonate inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect .
    Icerguastat Carbonate

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