1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. (E)-Guanabenz

(E)-Guanabenz (Synonyms: (E)-Wy-8678)

Cat. No.: HY-W263279
Handling Instructions

(E)-Guanabenz ((E)-Wy-8678) is an orally active central α2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity, acts via stimulating central α2-adrenoceptors, and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34, and has neuroprotective activity. (E)-Guanabenz can be used for researching hypertension and Parkinson disease.

For research use only. We do not sell to patients.

(E)-Guanabenz Chemical Structure

(E)-Guanabenz Chemical Structure

CAS No. : 60329-03-5

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Description

(E)-Guanabenz ((E)-Wy-8678) is an orally active central α2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity, acts via stimulating central α2-adrenoceptors, and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34, and has neuroprotective activity. (E)-Guanabenz can be used for researching hypertension and Parkinson disease[1][2].

IC50 & Target

α2-adrenoceptor, GADD34[1][2]

Molecular Weight

231.08

Formula

C8H8Cl2N4

CAS No.
SMILES

ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.[(E)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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(E)-Guanabenz
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