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Results for "

JAK+inhibitor+I

" in MedChemExpress (MCE) Product Catalog:
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Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-14435
    Pyridone 6
    10+ Cited Publications

    		 JAK Cancer
    Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.
    Pyridone 6
  • HY-159536
    Frevecitinib

    KN-002; VR-588

    		 JAK Inflammation/Immunology
    Frevecitinib (KN-002) is a potent pan-JAK inhibitor (i.e. JAK1, JAK2, JAK3, TYK2). Frevecitinib can be used for the study of asthma and other respiratory conditions such as chronic obstructive pulmonary disease (COPD).
    Frevecitinib

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