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Mirvetuximab soravtansine (solution)

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-132258A
    Mirvetuximab soravtansine (solution)
    3 Publications Verification

    IMGN853 (solution)

    Antibody-Drug Conjugates (ADCs) Antifolate Cancer
    Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage .
    Mirvetuximab soravtansine (solution)

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