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TP53

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Cat. No. Compare Product Name Species Source
  • HY-P71703
    p53 Protein, Rat (His)

    TP53; P53; Cellular tumor antigen p53; Tumor suppressor p53

    		 Rat E. coli
    The p53 protein acts as a tumor suppressor, regulating the cell cycle and inducing growth arrest or apoptosis. It activates genes that inhibit cell division and triggers apoptosis by controlling the expression of various proteins. It interacts with different proteins to facilitate pro-apoptotic function, but its activity can be inhibited by other proteins. Additionally, p53 is involved in oxidative stress-induced necrosis and prevents CDK7 kinase activity in response to DNA damage. It also induces the transcription of specific non-coding RNAs and regulates the circadian clock. p53 Protein, Rat (His) is the recombinant rat-derived p53 protein, expressed by E. coli, with N-6*His labeled tag. The total length of p53 Protein, Rat (His) is 391 a.a., with molecular weight of ~50 kDa.

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