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Results for "

Temozolomide (Standard)

" in MedChemExpress (MCE) Product Catalog:
Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-B0106R
    Levetiracetam (Standard)

    UCB L059 (Standard)

    		 Reference Standards DNA Methyltransferase Neurological Disease Cancer
    Levetiracetam (Standard) is the analytical standard of Levetiracetam. This product is intended for research and analytical applications. Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent .
    Levetiracetam (Standard)
  • HY-17364R
    Temozolomide (Standard)

    NSC 362856 (Standard); CCRG 81045 (Standard); TMZ (Standard)

    		 Reference Standards DNA Alkylator/Crosslinker Autophagy Apoptosis Cancer
    Temozolomide (Standard) is the analytical standard of Temozolomide. This product is intended for research and analytical applications. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects .
    Temozolomide (Standard)
  • HY-12772R
    Hydroxy Itraconazole (Standard)

    Itraconazole metabolite Hydroxy Itraconazole (Standard); R-63373 (Standard)

    		 Reference Standards Fungal Drug Metabolite Others
    Levetiracetam (Standard) is the analytical standard of Levetiracetam. This product is intended for research and analytical applications. Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent .
    Hydroxy Itraconazole (Standard)
  • HY-119696R
    MTIC (Standard)

    		Reference Standards Drug Metabolite Neurological Disease Cancer
    MTIC (Standard) is the analytical standard of MTIC. This product is intended for research and analytical applications. MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity [1][2][3][4].
    MTIC (Standard)
  • HY-10261BR
    (E/Z)-Afatinib (Standard)

    (E/Z)-BIBW 2992 (Standard)

    		 EGFR Apoptosis c-Met/HGFR Akt p38 MAPK Autophagy Reference Standards Others
    (E/Z)-Afatinib (Standard) is the analytical standard of (E/Z)-Afatinib. This product is intended for research and analytical applications. (E/Z)-Afatinib ((E/Z)-BIBW 2992) is the mixture of (E)-Afatinib and (Z)-Afatinib. Afatinib (HY-10261) is an irreversible inhibitor of EGFR, by irreversibly binding to their ATP binding site to block activation of EGFR, HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide (HY-17364), potently targeting to EGFRvIII-cMet signaling in glioblastoma cells .
    (E/Z)-Afatinib (Standard)

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