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Viloxazine

" in MedChemExpress (MCE) Product Catalog:

8

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3

同位体標識化合物

製品番号 製品名 Target 研究分野 構造式
  • HY-W380450
    Viloxazine

    Viloxazin; Emovit

    		 5-HT Receptor Neurological Disease
    Viloxazine is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor (IC50= 0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors (Ki=4.2 μM) and agonizes 5-HT2C receptors (EC50= 32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD) .
    Viloxazine
  • HY-125784
    Viloxazine hydrochloride

    Viloxazin hydrochloride; Emovit hydrochloride

    		 5-HT Receptor Neurological Disease
    Viloxazine hydrochloride is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor (IC50=0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors (Ki=4.2 μM) and agonizes 5-HT2C receptors (EC50=32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD) .
    Viloxazine hydrochloride
  • HY-125784A
    (R)-Viloxazine hydrochloride

    		5-HT Receptor Neurological Disease
    (R)-Viloxazine hydrochloride is a less active R-isomer of Viloxazine hydrochloride. Viloxazine hydrochloride is an effective antidepressant agent .
    (R)-Viloxazine hydrochloride
  • HY-125784B
    (S)-Viloxazine hydrochloride

    (S)-Viloxazin hydrochloride; (S)-Emovit hydrochloride

    		 Drug Isomer Adrenergic Receptor Neurological Disease
    (S)-Viloxazine hydrochloride is the isomer of Viloxazine hydrochloride (HY-125784). Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist，EC50 for 5-HT2C b> is 32 μM，and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research .
    (S)-Viloxazine hydrochloride
  • HY-125784S
    (rac)-Viloxazine-d5 hydrochloride

    		Isotope-Labeled Compounds Others
    (rac)-Viloxazine-d5 (hydrochloride) is the deuterium labeled (rac)-Viloxazine hydrochloride .
    (rac)-Viloxazine-d5 hydrochloride
  • HY-125784BS
    (S)-Viloxazine-d5 hydrochloride

    		Isotope-Labeled Compounds Others
    (S)-Viloxazine-d5 (hydrochloride) is the deuterium labeled (S)-Viloxazine hydrochloride .
    (S)-Viloxazine-d5 hydrochloride
  • HY-125784AS
    (R)-Viloxazine-d5 hydrochloride

    (R)-Viloxazin-d5 hydrochloride; (R)-Emovit-d5 hydrochloride

    		 Isotope-Labeled Compounds Others
    (R)-Viloxazine-d5 hydrochloride is the deuterium labeled (R)-Viloxazine hydrochloride .
    (R)-Viloxazine-d5 hydrochloride
  • HY-W380450R
    Viloxazine (Standard)

    Viloxazin (Standard); Emovit (Standard)

    		 Reference Standards 5-HT Receptor Neurological Disease
    Viloxazine is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor (IC50= 0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors (Ki=4.2 μM) and agonizes 5-HT2C receptors (EC50= 32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD) .
    Viloxazine (Standard)

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