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Results for "

YWHAH

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

1

Antibodies

Cat. No. Compare Product Name Species Source
  • HY-P71682
    YWHAH Protein, Human (GST)

    14-3-3 protein eta; Brain protein 14-3-3; eta isoform; HGNC:12853; Protein AS1; YWHA 1; YWHA1; YWHAH

    		 Human E. coli
    YWHAH protein, an adapter in diverse signaling pathways, recognizes phosphoserine or phosphothreonine motifs, modulating partner activity upon binding. It negatively regulates PDPK1 kinase activity and interacts with nuclear hormone receptors (AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP, THRA) and cofactors. Additionally, it interacts with phosphorylated ABL1, retaining it in the cytoplasm, and weakly with CDKN1B. Interactions involve ARHGEF28, CDK16, GAB2, KCNK18 (phosphorylation-dependent), SAMSN1, phosphorylated PDPK1, phosphorylated DAPK2, PI4KB, TBC1D22A, TBC1D22B, SLITRK1, and MEFV, highlighting its multifunctional role. YWHAH Protein, Human (GST) is the recombinant human-derived YWHAH protein, expressed by E. coli, with N-GST labeled tag. The total length of YWHAH Protein, Human (GST) is 243 a.a., with molecular weight of ~54.9 kDa.

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