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Results for "

frameshifting

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Fluorescent Dye

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139010
    Merafloxacin

    CI-934

    		 SARS-CoV Infection
    Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin exhibits in vitro activity against gram-positive and gram-negative bacteria .
    Merafloxacin
  • HY-D0344
    Giuba Black D

    Direct Black 17

    		 Fluorescent Dye Others
    Direct Grey D exhibits frameshift mutagenic activity .
    Giuba Black D
  • HY-157848
    SARS-CoV-2-IN-82

    		SARS-CoV Infection
    SARS-CoV-2-IN-82 (compound A) is a Programmed-1 ribosomal frameshift (-1 PRF) inhibitor of SARS-CoV-2 .
    SARS-CoV-2-IN-82
  • HY-W728005
    Covidcil-19

    		SARS-CoV Infection
    Covidcil-19 (compound C5) avidly binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with a Kd of 11 nM. Covidcil-19 stabilizes the hairpin’s folded state and impairs frameshifting in cells. Covidcil-19 reduces frameshifting efficiency of the SARS-CoV-2 FSE and does not affect SARS-CoV-2 FSE RNA levels. Covidcil-19 inhibits a process essential for SARS-CoV-2 viral propagation .
    Covidcil-19

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